Triterpenoids have been proven to activate AMPK [4] and activated AMPK can phosphorylate/acetylate FoxO1 to suppress hepatic gluconeogenesis
Liver lysates from mice had been immunoblotted with HAT1, phosphorylated (p-) and whole (t-) HDAC four and 5 (Class IIa HDACs) and quantified for statistical investigation. Changes in Class I…