N the other hand, in ethnicities, with sample-sizes of 30-55 individuals, the highest incidence of consanguinity was observed in Bains-Rajput (76.09 ), followed by Mughal (70.21 ), Syed (65.71 ), and Malik (64.81 ) (Table 1). Ornipressin site Within the ethnicities, differences in the number of CU and NCU were statistically significant (2=29.64, df.9; p=0.0005) (Table 1).Age of subjectsThe highest incidence of CU was observed in the subjects belonging to the age-range of 16-19 years (75 ; ICF=0.0441), followed by 20-29 years (64.26 ; ICF=0.0359) (Table 1). There was a declining trend in CU and ICF with respect to the increasing subject’s age. Differences in the distribution of CU and NCU with respect to age categories were statistically significant (Table 1).Mother tongueWith respect to the mother tongue, majority of the subjects were Punjabi-speaking (n=1071; 67.61 ) while there were 513 (32.39 ) subjects speaking Pahari (Table 1). The incidence of CU was higher in subjects speaking Pahari language compared to subjects speaking Punjabi (67.81 vs 59.48 respectively). First-cousin unions were 53.61 in Pahari-speaking subjects compared to 48.46 in the Punjabi-speaking individuals (Table 2).Ethnicity/caste groupsThe largest representatives belonged to Jatt community (n=674), followed by Rajput, Gujjar, and Mirza (n=227, 221, and 193 respectively) (Table 1). Among these four major buy HIV-1 integrase inhibitor 2 ethnicities (i.e. samplesize >190), the highest rate of CU was witnessed in Jatt (67.36 ), followed by Mirza (58.03 ) and Rajput (57.71 ) (Table 1). First-cousin (FC) marriagesVolume 32 | Number 2 | JuneRural/urban statusMajority of the subjects originated from rural areas (85.29 ; n=1,351), followed by subjects belonging to peri-urban (9.6 ) and urban (5.11 ) areas (Table 1). The proposition of CU was slightly higher in the peri-urban sample (62.03 ) compared to the rural and urban cohorts.Consanguinity in Bhimber, Azad Kashmir, PakistanJabeen N and Malik STable 2. Relative percentages of different marriage types across various demographic parameters Consanguineous ( ) Parameter DFC FC FCOR SC Non-consanguineous ( ) Second cousin once removed 3.24 1.54 0.39 1.83 29 0.00 1.26 2.16 2.46 1.42 3.57 2.08 0.88 0.45 4.15 0 2.13 0 0 0 5.36 2.52 0.39 2.07 0.66 0 3.08 0.89 3.77 0 DisNontantly related related Total no.Tehsil Bhimber Barnala Samahni Total ( ) Total (No.) Age interval (completed years) 16-19 20-29 30-39 40-49 50-59 60 and above Ethnic origin (husband) Jatt Rajput Gujjar Mirza Malik Mughal Bains-Rajput Syed Butt Others (n<30) Mother tongue Punjabi Pahari Location Rural Peri-urban Urban Family structure Nuclear family Extended family (all) One couple and grandparents More than one couple 0.59 1.00 0.94 0 43.47 55.15 50.94 25.00 5.14 3.54 3.77 12.50 7.49 6.64 11.32 25.00 17.77 14.62 15.09 0 22.47 18.16 14.15 37.50 681 903 106 16 Contd.306 JHPN0.49 1.54 0.58 0.82 13 2.50 0.72 0.39 0.35 2.84 1.79 0.74 0 1.81 0 3.7 2.13 2.17 0 0 0 0.93 0.58 0.81 0 2.50.57 45.59 53.61 50.13 794 62.50 51.81 50.69 52.11 41.84 30.36 55.19 47.58 42.99 47.67 40.74 59.57 58.70 45.71 29.03 44.64 48.46 53.61 49.52 56.58 48.4.70 2.86 4.87 4.23 67 2.50 5.05 4.91 3.52 1.42 1.79 4.45 3.08 2.71 6.22 5.56 4.26 2.17 5.71 6.45 3.57 3.92 4.87 4.44 3.95 1.7.29 4.63 8.77 7.01 111 7.50 6.68 7.86 6.34 6.38 7.14 6.97 7.05 3.62 4.15 14.81 4.26 13.04 14.29 16.13 10.71 6.16 8.77 7.25 3.29 9.15.88 14.98 16.96 15.97 253 10.00 13.72 14.54 15.85 21.99 41.07 12.76 21.15 14.03 20.73 14.81 10.64 15.22 22.86 29.03 19.64 15.50 1.N the other hand, in ethnicities, with sample-sizes of 30-55 individuals, the highest incidence of consanguinity was observed in Bains-Rajput (76.09 ), followed by Mughal (70.21 ), Syed (65.71 ), and Malik (64.81 ) (Table 1). Within the ethnicities, differences in the number of CU and NCU were statistically significant (2=29.64, df.9; p=0.0005) (Table 1).Age of subjectsThe highest incidence of CU was observed in the subjects belonging to the age-range of 16-19 years (75 ; ICF=0.0441), followed by 20-29 years (64.26 ; ICF=0.0359) (Table 1). There was a declining trend in CU and ICF with respect to the increasing subject's age. Differences in the distribution of CU and NCU with respect to age categories were statistically significant (Table 1).Mother tongueWith respect to the mother tongue, majority of the subjects were Punjabi-speaking (n=1071; 67.61 ) while there were 513 (32.39 ) subjects speaking Pahari (Table 1). The incidence of CU was higher in subjects speaking Pahari language compared to subjects speaking Punjabi (67.81 vs 59.48 respectively). First-cousin unions were 53.61 in Pahari-speaking subjects compared to 48.46 in the Punjabi-speaking individuals (Table 2).Ethnicity/caste groupsThe largest representatives belonged to Jatt community (n=674), followed by Rajput, Gujjar, and Mirza (n=227, 221, and 193 respectively) (Table 1). Among these four major ethnicities (i.e. samplesize >190), the highest rate of CU was witnessed in Jatt (67.36 ), followed by Mirza (58.03 ) and Rajput (57.71 ) (Table 1). First-cousin (FC) marriagesVolume 32 | Number 2 | JuneRural/urban statusMajority of the subjects originated from rural areas (85.29 ; n=1,351), followed by subjects belonging to peri-urban (9.6 ) and urban (5.11 ) areas (Table 1). The proposition of CU was slightly higher in the peri-urban sample (62.03 ) compared to the rural and urban cohorts.Consanguinity in Bhimber, Azad Kashmir, PakistanJabeen N and Malik STable 2. Relative percentages of different marriage types across various demographic parameters Consanguineous ( ) Parameter DFC FC FCOR SC Non-consanguineous ( ) Second cousin once removed 3.24 1.54 0.39 1.83 29 0.00 1.26 2.16 2.46 1.42 3.57 2.08 0.88 0.45 4.15 0 2.13 0 0 0 5.36 2.52 0.39 2.07 0.66 0 3.08 0.89 3.77 0 DisNontantly related related Total no.Tehsil Bhimber Barnala Samahni Total ( ) Total (No.) Age interval (completed years) 16-19 20-29 30-39 40-49 50-59 60 and above Ethnic origin (husband) Jatt Rajput Gujjar Mirza Malik Mughal Bains-Rajput Syed Butt Others (n<30) Mother tongue Punjabi Pahari Location Rural Peri-urban Urban Family structure Nuclear family Extended family (all) One couple and grandparents More than one couple 0.59 1.00 0.94 0 43.47 55.15 50.94 25.00 5.14 3.54 3.77 12.50 7.49 6.64 11.32 25.00 17.77 14.62 15.09 0 22.47 18.16 14.15 37.50 681 903 106 16 Contd.306 JHPN0.49 1.54 0.58 0.82 13 2.50 0.72 0.39 0.35 2.84 1.79 0.74 0 1.81 0 3.7 2.13 2.17 0 0 0 0.93 0.58 0.81 0 2.50.57 45.59 53.61 50.13 794 62.50 51.81 50.69 52.11 41.84 30.36 55.19 47.58 42.99 47.67 40.74 59.57 58.70 45.71 29.03 44.64 48.46 53.61 49.52 56.58 48.4.70 2.86 4.87 4.23 67 2.50 5.05 4.91 3.52 1.42 1.79 4.45 3.08 2.71 6.22 5.56 4.26 2.17 5.71 6.45 3.57 3.92 4.87 4.44 3.95 1.7.29 4.63 8.77 7.01 111 7.50 6.68 7.86 6.34 6.38 7.14 6.97 7.05 3.62 4.15 14.81 4.26 13.04 14.29 16.13 10.71 6.16 8.77 7.25 3.29 9.15.88 14.98 16.96 15.97 253 10.00 13.72 14.54 15.85 21.99 41.07 12.76 21.15 14.03 20.73 14.81 10.64 15.22 22.86 29.03 19.64 15.50 1.