Product Name :
Fenbufen-d9
Description:
Fenbufen-d9 (CL-82204-d9) is the deuterium labeled Fenbufen. Fenbufen (CL-82204) is an orally active non-steroidal anti-inflammatory drug (NSAID), with analgetic and antipyretic effects. Fenbufen has potent activity in a variety of animal model, including carageenin edema, UV erythema and adjuvant arthritis. Fenbufen has inhibitory activities against COX-1 and COX-2 with IC50s of 3.9 μM and 8.1 μM, respectively. Fenbufen is a caspases (caspase-1, 3, 4, 5, 9) inhibitor.
CAS:
1189940-96-2
Molecular Weight:
263.34
Formula:
C16H14O3
Chemical Name:
4-[(2,2′,3,3′,4′,5,5′,6,6′-²H₉)-[1,1′-biphenyl]-4-yl]-4-oxobutanoic acid
Smiles :
[2H]C1=C(C(=O)CCC(O)=O)C([2H])=C([2H])C(C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])=C1[2H]
InChiKey:
ZPAKPRAICRBAOD-LOIXRAQWSA-N
InChi :
InChI=1S/C16H14O3/c17-15(10-11-16(18)19)14-8-6-13(7-9-14)12-4-2-1-3-5-12/h1-9H,10-11H2,(H,18,19)/i1D,2D,3D,4D,5D,6D,7D,8D,9D
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Arbutin} medchemexpress|{Arbutin} Endogenous Metabolite|{Arbutin} Protocol|{Arbutin} In Vitro|{Arbutin} supplier|{Arbutin} Autophagy}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Fenbufen-d9 (CL-82204-d9) is the deuterium labeled Fenbufen. Fenbufen (CL-82204) is an orally active non-steroidal anti-inflammatory drug (NSAID), with analgetic and antipyretic effects. Fenbufen has potent activity in a variety of animal model, including carageenin edema, UV erythema and adjuvant arthritis. Fenbufen has inhibitory activities against COX-1 and COX-2 with IC50s of 3.9 μM and 8.1 μM, respectively. Fenbufen is a caspases (caspase-1, 3, 4, 5, 9) inhibitor.|Product information|CAS Number: 1189940-96-2|Molecular Weight: 263.34|Formula: C16H14O3|Chemical Name: 4-[(2,2′,3,3′,4′,5,5′,6,6′-²H₉)-[1,1′-biphenyl]-4-yl]-4-oxobutanoic acid|Smiles: [2H]C1=C(C(=O)CCC(O)=O)C([2H])=C([2H])C(C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])=C1[2H]|InChiKey: ZPAKPRAICRBAOD-LOIXRAQWSA-N|InChi: InChI=1S/C16H14O3/c17-15(10-11-16(18)19)14-8-6-13(7-9-14)12-4-2-1-3-5-12/h1-9H,10-11H2,(H,18,19)/i1D,2D,3D,4D,5D,6D,7D,8D,9D|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Ozoralizumab} MedChemExpress|{Ozoralizumab} Apoptosis|{Ozoralizumab} Biological Activity|{Ozoralizumab} References|{Ozoralizumab} supplier|{Ozoralizumab} Cancer} |Shelf Life: ≥12 months if stored properly.PMID:35670838 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.|Products are for research use only. Not for human use.|