Product Name :
TH 257
Description:
TH-257 is a selective LIMK inhibitor with IC50 values of 84nM and 39nM for LIMK1 and LIMK2, respectively.
CAS:
2244678-29-1
Molecular Weight:
422.54
Formula:
C24H26N2O3S
Chemical Name:
N-Butyl-4-[(phenylamino)sulfonyl]-N-(phenylmethyl)benzamide
Smiles :
CCCCN(CC1C=CC=CC=1)C(=O)C1C=CC(=CC=1)S(=O)(=O)NC1C=CC=CC=1
InChiKey:
VNCIWNGCMAKKEO-UHFFFAOYSA-N
InChi :
InChI=1S/C24H26N2O3S/c1-2-3-18-26(19-20-10-6-4-7-11-20)24(27)21-14-16-23(17-15-21)30(28,29)25-22-12-8-5-9-13-22/h4-17,25H,2-3,18-19H2,1H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Valacyclovir} site|{Valacyclovir} Anti-infection|{Valacyclovir} Biological Activity|{Valacyclovir} References|{Valacyclovir} manufacturer|{Valacyclovir} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.{{Darovasertib} web|{Darovasertib} PKC|{Darovasertib} Technical Information|{Darovasertib} In Vivo|{Darovasertib} supplier|{Darovasertib} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:35345980
Additional information:
TH-257 is a selective LIMK inhibitor with IC50 values of 84nM and 39nM for LIMK1 and LIMK2, respectively.|Product information|CAS Number: 2244678-29-1|Molecular Weight: 422.54|Formula: C24H26N2O3S|Chemical Name: N-Butyl-4-[(phenylamino)sulfonyl]-N-(phenylmethyl)benzamide|Smiles: CCCCN(CC1C=CC=CC=1)C(=O)C1C=CC(=CC=1)S(=O)(=O)NC1C=CC=CC=1|InChiKey: VNCIWNGCMAKKEO-UHFFFAOYSA-N|InChi: InChI=1S/C24H26N2O3S/c1-2-3-18-26(19-20-10-6-4-7-11-20)24(27)21-14-16-23(17-15-21)30(28,29)25-22-12-8-5-9-13-22/h4-17,25H,2-3,18-19H2,1H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 250 mg/mL (591.66 mM; Need ultrasonic)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Manetti F. Recent advances in the rational design and development of LIM kinase inhibitors are not enough to enter clinical trials. Eur J Med Chem. 2018 Jul 15;155:445-458.Products are for research use only. Not for human use.|