Product Name :
RG3039
Description:
RG3039 (PF-06687859, PF 6687859, Quinazoline 495) is an orally bioavailable and brain-penetrant inhibitor of the mRNA decapping enzyme DcpS with IC50 of 4.2 nM and IC90 of 40 nM, respectively.
CAS:
1005504-62-0
Molecular Weight:
432.35
Formula:
C21H23Cl2N5O
Chemical Name:
5-((1-(2,6-dichlorobenzyl)piperidin-4-yl)methoxy)quinazoline-2,4-diamine
Smiles :
NC1=NC(N)=NC2=CC=CC(OCC3CCN(CC4C(Cl)=CC=CC=4Cl)CC3)=C12
InChiKey:
MNLHFGXIUJNDAF-UHFFFAOYSA-N
InChi :
InChI=1S/C21H23Cl2N5O/c22-15-3-1-4-16(23)14(15)11-28-9-7-13(8-10-28)12-29-18-6-2-5-17-19(18)20(24)27-21(25)26-17/h1-6,13H,7-12H2,(H4,24,25,26,27)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Fmoc-Pro-OH} web|{Fmoc-Pro-OH} {Amino Acid Derivatives}|{Fmoc-Pro-OH} Purity & Documentation|{Fmoc-Pro-OH} Data Sheet|{Fmoc-Pro-OH} manufacturer|{Fmoc-Pro-OH} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
RG3039 (PF-06687859, PF 6687859, Quinazoline 495) is an orally bioavailable and brain-penetrant inhibitor of the mRNA decapping enzyme DcpS with IC50 of 4.2 nM and IC90 of 40 nM, respectively.|Product information|CAS Number: 1005504-62-0|Molecular Weight: 432.{{Temsirolimus} web|{Temsirolimus} Anti-infection|{Temsirolimus} Purity & Documentation|{Temsirolimus} In Vivo|{Temsirolimus} supplier|{Temsirolimus} Autophagy} 35|Formula: C21H23Cl2N5O|Synonym:|PF-06687859|Chemical Name: 5-((1-(2,6-dichlorobenzyl)piperidin-4-yl)methoxy)quinazoline-2,4-diamine|Smiles: NC1=NC(N)=NC2=CC=CC(OCC3CCN(CC4C(Cl)=CC=CC=4Cl)CC3)=C12|InChiKey: MNLHFGXIUJNDAF-UHFFFAOYSA-N|InChi: InChI=1S/C21H23Cl2N5O/c22-15-3-1-4-16(23)14(15)11-28-9-7-13(8-10-28)12-29-18-6-2-5-17-19(18)20(24)27-21(25)26-17/h1-6,13H,7-12H2,(H4,24,25,26,27)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO: 3 mg/mL(6.PMID:23614016 93 mM).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Rocky G Gogliotti, et al. Hum Mol Genet. 2013 Oct 15;22(20):4084-101.Products are for research use only. Not for human use.|