Product Name :
Aztreonam
Description:
Aztreonam is a monobactam antibiotic used primarily to treat infections caused by gram-negative bacteria. Aztreonam is a monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum with bactericidal activity. Aztreonam preferentially binds to and inactivates penicillin-binding protein-3 (PBP-3), which is involved in bacterial cell wall synthesis, thereby inhibiting bacterial cell wall integrity and leading to cell lysis and death. This agent differs from other beta-lactam antibiotics because it is resistant to beta-lactamase hydrolysis, and it is usually used to treat infections caused by gram-negative aerobic microorganisms.
CAS:
78110-38-0
Molecular Weight:
435.43
Formula:
C13H17N5O8S2
Chemical Name:
2-{[(Z)-[(2-amino-1,3-thiazol-4-yl)({[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]carbamoyl})methylidene]amino]oxy}-2-methylpropanoic acid
Smiles :
C[C@H]1[C@H](NC(=O)/C(=N\OC(C)(C)C(O)=O)/C2=CSC(N)=N2)C(=O)N1S(O)(=O)=O
InChiKey:
WZPBZJONDBGPKJ-VEHQQRBSSA-N
InChi :
InChI=1S/C13H17N5O8S2/c1-5-7(10(20)18(5)28(23,24)25)16-9(19)8(6-4-27-12(14)15-6)17-26-13(2,3)11(21)22/h4-5,7H,1-3H3,(H2,14,15)(H,16,19)(H,21,22)(H,23,24,25)/b17-8-/t5-,7-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Peramivir} web|{Peramivir} NF-κB|{Peramivir} Technical Information|{Peramivir} Purity|{Peramivir} manufacturer|{Peramivir} Epigenetics}
Shelf Life:
≥360 days if stored properly.{{SCF Protein, Mouse} MedChemExpress|{SCF Protein, Mouse} Technical Information|{SCF Protein, Mouse} Purity|{SCF Protein, Mouse} supplier|{SCF Protein, Mouse} Epigenetics}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24914310
Additional information:
Aztreonam is a monobactam antibiotic used primarily to treat infections caused by gram-negative bacteria. Aztreonam is a monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum with bactericidal activity. Aztreonam preferentially binds to and inactivates penicillin-binding protein-3 (PBP-3), which is involved in bacterial cell wall synthesis, thereby inhibiting bacterial cell wall integrity and leading to cell lysis and death. This agent differs from other beta-lactam antibiotics because it is resistant to beta-lactamase hydrolysis, and it is usually used to treat infections caused by gram-negative aerobic microorganisms.|Product information|CAS Number: 78110-38-0|Molecular Weight: 435.43|Formula: C13H17N5O8S2|Chemical Name: 2-{[(Z)-[(2-amino-1,3-thiazol-4-yl)({[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]carbamoyl})methylidene]amino]oxy}-2-methylpropanoic acid|Smiles: C[C@H]1[C@H](NC(=O)/C(=N\OC(C)(C)C(O)=O)/C2=CSC(N)=N2)C(=O)N1S(O)(=O)=O|InChiKey: WZPBZJONDBGPKJ-VEHQQRBSSA-N|InChi: InChI=1S/C13H17N5O8S2/c1-5-7(10(20)18(5)28(23,24)25)16-9(19)8(6-4-27-12(14)15-6)17-26-13(2,3)11(21)22/h4-5,7H,1-3H3,(H2,14,15)(H,16,19)(H,21,22)(H,23,24,25)/b17-8-/t5-,7-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|