Product Name :
Anti-LILRB4, Human antibody
Applications:
ELISA,Flow Cyt
Reactivity :
Human
Conjugate:
Unconjugated
Advantages :
High lot-to-lot consistencyIncreased sensitivity and higher affinityAnimal-free production
Description:
| Description: Anti-LILRB4, Human antibody is designed for detecting human LILRB4 specifically. Based on ELISA and/or FCM, Anti-LILRB4, Human antibody reacts with human LILRB4 specifically. | Immunogen: Recombinant human LILRB4 | Host: Alpaca pacous | Isotype: Human IgG1 | Conjugate: Unconjugated | Specificity: Human LILRB4 | Purity: Recombinant Expression and Affinity purified | Concentration: 1mg/ml | Formation: Liquid, 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% Glycerol | Storage: Store at –20 °C, (Avoid freeze / thaw cycles) | Background:This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation.{{86694-45-3} site|{86694-45-3} Biological Activity|{86694-45-3} In Vitro|{86694-45-3} custom synthesis} It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity.{{571190-30-2} site|{571190-30-2} Purity & Documentation|{571190-30-2} In Vivo|{571190-30-2} supplier} Multiple transcript variants encoding different isoforms have been found for this gene.PMID:29999714
Description2 :
Anti-LILRB4, Human antibody is designed for detecting human LILRB4 specifically. Based on ELISA and/or FCM, Anti-LILRB4, Human antibody reacts with human LILRB4 specifically.
Immunogen:
Recombinant human LILRB4
Host :
Alpaca pacous
Isotype:
Human IgG1
Purity :
Recombinant Expression and Affinity purified
Buffer :
Storage :
Store at –20 °C, (Avoid freeze / thaw cycles)
Function:
ELISA: 1:4,000-1:10000Flow Cytometry：1:200-1:1000Dilution factors are presented in the form of a range because the optimal dilution is a function of many factors, such as antigen density, permeability, etc. The actual dilution used must be determined empirically.