Product Name :
MKP-5 (human), (recombinant) (His-tag)
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Molecular Weight:
53 kDa
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Description:
MKP-5 (DUSP10) is a member of a group of dual specificity phosphatases which negatively regulate MAP kinases, dephosphorylating both the phosphotyrosine and phosphothreonine in the pTXpY activation loop motif. MKP5 has a principal function in both innate and adaptive immune responses. SDS-PAGE Analysis. Lane 1: MW Marker, Lane 2: 1.0µg of purified MKP-5 (human) (recombinant) (His-tag). SDS-PAGE Analysis. Lane 1: MW Marker, Lane 2: 1.0µg of purified MKP-5 (human) (recombinant) (His-tag).
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Additional Information :
| Alternative Name MAP kinase phosphatase 5, DUSP10, Dual specificity protein phosphatase 10 | Formulation Liquid. In 20mM TRIS/HCl, pH 8.{{1523406-39-4} web|{1523406-39-4} Technical Information|{1523406-39-4} In stock|{1523406-39-4} supplier} 0, 200mM NaCl, 5mM DTT, 0.{{2704602-92-4} site|{2704602-92-4} Protocol|{2704602-92-4} References|{2704602-92-4} supplier} 1 % Tween-20, 10% glycerol.PMID:25905215 | Gene/Protein Identifier NM_007207 (RefSeq) | MW 53 kDa | Purity Detail Partially purified by single-step affinity chromatography and gel filtration. | Source Produced in Sf9 insect cells. Recombinant human MKP-5 fused at the N-terminus to a His-tag. Produced in a baculovirus expression system. | Specific Activity ≥50 U/mg assayed by 3-O-methyl fluorescein phosphate (OMFP) hydrolysis at pH 8.2, 30°C. One unit is equal to 1 nmole phosphate hydrolyzed from OMFP per minute. | UniProt ID Q9Y6W6