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SAP97 monoclonal antibody (RPI 197.4)
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Synapse-associated proteins SAP97 and SAP102 display extensive sequence homology to the PSD 95 family of proteins that facilitate ion channel clustering at synaptic terminals. In addition to the CNS, SAP97 is also detected at the basal lateral membrane between a variety of epithelial cells. SAP102 associates with NMDA receptors through the C-terminal NR2B subunit of the receptor.865854-05-3 site The N-terminal SAP97 PDZ domain mediates its interaction with the synaptic ras-GTPase activating protein SynGAP. Western blot analysis: Lane 1: MW marker, Lane 2: Rat Brain Tissue Extract, Lane 3: Mouse Brain Tissue Extract.259793-96-9 Technical Information Western blot analysis: Lane 1: MW marker, Lane 2: Rat Brain Tissue Extract, Lane 3: Mouse Brain Tissue Extract.
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| Alternative Name Synapse-associated protein 97, Disks large homolog 1 | Application ICC, IHC, IP, WB | Application Notes Detects bands of ~97kDa and ~140kDa by Western blot.PMID:30521291 | Clone RPI 197.4 | Formulation Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide. | Host Mouse | Immunogen Recombinant rat SAP97 (N-terminal fragment). | Isotype IgG1 | Recommendation Dilutions/Conditions Western Blot (1:1,000, ECL)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application. | Source Purified from ascites. | Species Reactivity Dog, Human, Mouse, Rat | UniProt ID Q62696 | Unit of Measure (UM) µg