Product Name :
RN-1747
Description:
RN-1747 is a selective TRPV4 agonist with EC50s of 0.77 μM, 4.0 μM and 4.1 μM for hTRPV4, mTRPV4 and rTRPV4, respectively. RN-1747 also antagonizes TRPM8 with IC50 of 4 μM.
CAS:
1024448-59-6
Molecular Weight:
395.86
Formula:
C17H18ClN3O4S
Chemical Name:
1-benzyl-4-(4-chloro-2-nitrobenzenesulfonyl)piperazine
Smiles :
[O-][N+](=O)C1=CC(Cl)=CC=C1S(=O)(=O)N1CCN(CC2C=CC=CC=2)CC1
InChiKey:
ZNLVYSJQUMALEO-UHFFFAOYSA-N
InChi :
InChI=1S/C17H18ClN3O4S/c18-15-6-7-17(16(12-15)21(22)23)26(24,25)20-10-8-19(9-11-20)13-14-4-2-1-3-5-14/h1-7,12H,8-11,13H2
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Tarlatamab manufacturer
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
RN-1747 is a selective TRPV4 agonist with EC50s of 0.77 μM, 4.0 μM and 4.1 μM for hTRPV4, mTRPV4 and rTRPV4, respectively. RN-1747 also antagonizes TRPM8 with IC50 of 4 μM.|Product information|CAS Number: 1024448-59-6|Molecular Weight: 395.Vasopressin Formula 86|Formula: C17H18ClN3O4S|Chemical Name: 1-benzyl-4-(4-chloro-2-nitrobenzenesulfonyl)piperazine|Smiles: [O-][N+](=O)C1=CC(Cl)=CC=C1S(=O)(=O)N1CCN(CC2C=CC=CC=2)CC1|InChiKey: ZNLVYSJQUMALEO-UHFFFAOYSA-N|InChi: InChI=1S/C17H18ClN3O4S/c18-15-6-7-17(16(12-15)21(22)23)26(24,25)20-10-8-19(9-11-20)13-14-4-2-1-3-5-14/h1-7,12H,8-11,13H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Solubility (25°C).PMID:32648236 DMSO: 79 mg/mL(199.56 mM). Water: Insoluble.|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|