Product Name :
Tropodifene
Description:
Tropodifene (Tropaphen) is an α-Adrenergic receptor inhibitor.
CAS:
15790-02-0
Molecular Weight:
407.50
Formula:
C25H29NO4
Chemical Name:
(1R,3S,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 3-[4-(acetyloxy)phenyl]-2-phenylpropanoate
Smiles :
CC(=O)OC1C=CC(CC(C(=O)O[C@@H]2C[C@@H]3CC[C@H](C2)N3C)C2C=CC=CC=2)=CC=1
InChiKey:
WYYRXLABEPJODI-ZLPMCDRXSA-N
InChi :
InChI=1S/C25H29NO4/c1-17(27)29-22-12-8-18(9-13-22)14-24(19-6-4-3-5-7-19)25(28)30-23-15-20-10-11-21(16-23)26(20)2/h3-9,12-13,20-21,23-24H,10-11,14-16H2,1-2H3/t20-,21+,23+,24?
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Tropodifene (Tropaphen) is an α-Adrenergic receptor inhibitor.|Product information|CAS Number: 15790-02-0|Molecular Weight: 407.50|Formula: C25H29NO4|Chemical Name: (1R,3S,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 3-[4-(acetyloxy)phenyl]-2-phenylpropanoate|Smiles: CC(=O)OC1C=CC(CC(C(=O)O[C@@H]2C[C@@H]3CC[C@H](C2)N3C)C2C=CC=CC=2)=CC=1|InChiKey: WYYRXLABEPJODI-ZLPMCDRXSA-N|InChi: InChI=1S/C25H29NO4/c1-17(27)29-22-12-8-18(9-13-22)14-24(19-6-4-3-5-7-19)25(28)30-23-15-20-10-11-21(16-23)26(20)2/h3-9,12-13,20-21,23-24H,10-11,14-16H2,1-2H3/t20-,21+,23+,24?|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.TRULI Activator |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.Lisaftoclax In Vitro |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Tropaphen has a beneficial effect on hypertension.PMID:32491513 The therapeutic effect of this preparation is more constant in diseases accompanied by spasm of the peripheral vessels. Tropaphen has a very marked adrenolytic and vasodilator action. It greatly lowers the tone of the peripheral vessels. The preparation is effective starting with a dose of 0.1 mg/kg. After injection of the drug in a dose of 0.25 mg/kg, a considerable and gradually progressive decrease in the perfusion pressure takes place. The pressure falls by 30-35% and remained at a low level for 90-100 min. With a dose of tropaphen of 0.5 mg/kg, the perfusion pressure falls by 40-45% and remains low for 120 min or more. Strong vasodilatation is also observed after injection of tropaphen into intact rabbits.|Products are for research use only. Not for human use.|