Product Name :
Rabbit anti-BCL2 Polyclonal Antibody
Synonym :
Bcl-2; PPP1R50
Host :
Rabbit
Species Reactivity:
Human, Mouse, Rat
Specificity :
Predicted Reactivity:
Applications :
WB 1:500 – 1:2000IHC 1:50 – 1:100IF 1:50 – 1:100
Immunogen:
A synthetic peptide of human BCL2
Concentration :
Purification :
Affinity purification
Clonality:
Polyclonal Antibody
Storage Temp.:
Store at -20 ℃Avoid freeze / that cycles
Research areas :
Background :
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.
UniProt :
P10415
Additional information:
Product Details FAQ Citations(1) Video Pictures Documents |Overview |Synonym Bcl-2; PPP1R50 |Host Rabbit |Species Reactivity Human, Mouse, Rat |Applications WB 1:500 – 1:2000IHC 1:50 – 1:100IF 1:50 – 1:100 |Immunogen A synthetic peptide of human BCL2 |Positive control Mouse liver,Rat liver |Properties |Purification Affinity purification |Clonality Polyclonal Antibody |Isotype IgG |Storage Temp. Store at -20 ℃Avoid freeze / that cycles |Storage Buffer Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |Target |Background This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. |Cellular localization Endoplasmic reticulum membrane,Mitochondrion outer membrane,Nucleus membrane,Single-pass membrane protein |UniProt P10415 |Tips:This product is for research use only. Not for use in diagnostic prodcedures.
Rabbit anti-BCL2 Polyclonal Antibody
Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.Related websites: https://www.medchemexpress.com/antibodies.html
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