Product Name :
Ioversol
Description:
Ioversol (MP-328) is a nonionic iodinated contrast medium (CM) that is used during a CT scan or x-ray in animal experiment. Ioversol does not damage the blood-brain barrier (BBB) in animal.
CAS:
87771-40-2
Molecular Weight:
807.11
Formula:
C18H24I3N3O9
Chemical Name:
N1,N3-bis(2,3-dihydroxypropyl)-5-[2-hydroxy-N-(2-hydroxyethyl)acetamido]-2,4,6-triiodobenzene-1,3-dicarboxamide
Smiles :
OCCN(C1C(I)=C(C(I)=C(C=1I)C(=O)NCC(O)CO)C(=O)NCC(O)CO)C(=O)CO
InChiKey:
AMDBBAQNWSUWGN-UHFFFAOYSA-N
InChi :
InChI=1S/C18H24I3N3O9/c19-13-11(17(32)22-3-8(29)5-26)14(20)16(24(1-2-25)10(31)7-28)15(21)12(13)18(33)23-4-9(30)6-27/h8-9,25-30H,1-7H2,(H,22,32)(H,23,33)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Ioversol (MP-328) is a nonionic iodinated contrast medium (CM) that is used during a CT scan or x-ray in animal experiment.{{Febuxostat} medchemexpress|{Febuxostat} Xanthine Oxidase|{Febuxostat} Protocol|{Febuxostat} In Vivo|{Febuxostat} custom synthesis|{Febuxostat} Autophagy} Ioversol does not damage the blood-brain barrier (BBB) in animal.|Product information|CAS Number: 87771-40-2|Molecular Weight: 807.11|Formula: C18H24I3N3O9|Chemical Name: N1,N3-bis(2,3-dihydroxypropyl)-5-[2-hydroxy-N-(2-hydroxyethyl)acetamido]-2,4,6-triiodobenzene-1,3-dicarboxamide|Smiles: OCCN(C1C(I)=C(C(I)=C(C=1I)C(=O)NCC(O)CO)C(=O)NCC(O)CO)C(=O)CO|InChiKey: AMDBBAQNWSUWGN-UHFFFAOYSA-N|InChi: InChI=1S/C18H24I3N3O9/c19-13-11(17(32)22-3-8(29)5-26)14(20)16(24(1-2-25)10(31)7-28)15(21)12(13)18(33)23-4-9(30)6-27/h8-9,25-30H,1-7H2,(H,22,32)(H,23,33)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : ≥ 100 mg/mL (123.90 mM).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Guselkumab} site|{Guselkumab} Immunology/Inflammation|{Guselkumab} Protocol|{Guselkumab} References|{Guselkumab} manufacturer|{Guselkumab} Epigenetic Reader Domain} |Shelf Life: ≥12 months if stored properly.PMID:29844565 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Ioversol (100 mg iodine/ml) exposure induces significantly increased lactate dehydrogenase release and decreased 3-(4,5-dimethyldiazol-2-yl)-2,5-diphenyl tetrazolium bromide conversion in NRK-52E cells. Ioversol significantly increases apoptosis and caspase-3 protein expression in the NRK-52E cells. Ioversol treatment induces a significant increase in [Ca2+]i and intracellular ROS.|In Vivo:|In comparison with iothalamate, Ioversol has a greatly reduced propensity to stimulate the release of endothelin, from cultured cells and when injected into anesthetized rats. Ioversol produces less renal vasoconstriction than does iothalamate, in control and in USIC rats, and the development of radiocontrast nephropathy, assessed by creatinine clearance and morphologic damage to the renal medulla, is largely avoided.|Products are for research use only. Not for human use.|