Product Name :
Batefenterol
Description:
Batefenterol (GSK961081, TD-5959) is both a muscarinic receptor antagonist and a β2-adrenoceptor agonist with Ki of 1.4 nM, 1.3 nM and 3.7 nM for hM2, hM3 muscarinic receptors and hβ2-adrenoceptor, respectively.
CAS:
743461-65-6
Molecular Weight:
740.24
Formula:
C40H42ClN5O7
Chemical Name:
(R)-1-(3-((2-chloro-4-(((2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethyl)amino)methyl)-5-methoxyphenyl)amino)-3-oxopropyl)piperidin-4-yl [1,1′-biphenyl]-2-ylcarbamate
Smiles :
COC1=CC(NC(=O)CCN2CCC(CC2)OC(=O)NC2=CC=CC=C2C2C=CC=CC=2)=C(Cl)C=C1CNC[C@H](O)C1=CC=C(O)C2NC(=O)C=CC=21
InChiKey:
URWYQGVSPQJGGB-DHUJRADRSA-N
InChi :
InChI=1S/C40H42ClN5O7/c1-52-36-22-33(31(41)21-26(36)23-42-24-35(48)29-11-13-34(47)39-30(29)12-14-37(49)45-39)43-38(50)17-20-46-18-15-27(16-19-46)53-40(51)44-32-10-6-5-9-28(32)25-7-3-2-4-8-25/h2-14,21-22,27,35,42,47-48H,15-20,23-24H2,1H3,(H,43,50)(H,44,51)(H,45,49)/t35-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Batefenterol (GSK961081, TD-5959) is both a muscarinic receptor antagonist and a β2-adrenoceptor agonist with Ki of 1.4 nM, 1.3 nM and 3.7 nM for hM2, hM3 muscarinic receptors and hβ2-adrenoceptor, respectively.|Product information|CAS Number: 743461-65-6|Molecular Weight: 740.24|Formula: C40H42ClN5O7|Synonym:|GSK961081|GSK-961081|GSK 961081|TD-5959|TD 5959|TD5959|Related CAS Number:|945905-37-3 (Batefenterol Succinate)|Chemical Name: (R)-1-(3-((2-chloro-4-(((2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethyl)amino)methyl)-5-methoxyphenyl)amino)-3-oxopropyl)piperidin-4-yl [1,1′-biphenyl]-2-ylcarbamate|Smiles: COC1=CC(NC(=O)CCN2CCC(CC2)OC(=O)NC2=CC=CC=C2C2C=CC=CC=2)=C(Cl)C=C1CNC[C@H](O)C1=CC=C(O)C2NC(=O)C=CC=21|InChiKey: URWYQGVSPQJGGB-DHUJRADRSA-N|InChi: InChI=1S/C40H42ClN5O7/c1-52-36-22-33(31(41)21-26(36)23-42-24-35(48)29-11-13-34(47)39-30(29)12-14-37(49)45-39)43-38(50)17-20-46-18-15-27(16-19-46)53-40(51)44-32-10-6-5-9-28(32)25-7-3-2-4-8-25/h2-14,21-22,27,35,42,47-48H,15-20,23-24H2,1H3,(H,43,50)(H,44,51)(H,45,49)/t35-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO: 100 mg/mL(135.{{Meropenem} MedChemExpress|{Meropenem} Anti-infection|{Meropenem} Biological Activity|{Meropenem} Description|{Meropenem} supplier|{Meropenem} Epigenetic Reader Domain} 09 mM).{{Fluphenazine} web|{Fluphenazine} Membrane Transporter/Ion Channel|{Fluphenazine} Protocol|{Fluphenazine} Purity|{Fluphenazine} supplier|{Fluphenazine} Autophagy} |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:24377291 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Sharath S Hegde, et al. J Pharmacol Exp Ther. 2014 Oct;351(1):190-9.Products are for research use only. Not for human use.|