Product Name :
LY2608204
Description:
LY-2608204 is an activator of glucokinase (GK) with an EC50 value of 42 nM. LY2608204 decreases plasma glucose in a dose-dependent manner at both fasted and postprandial glucose levels. In 2010, LY-2608204 was entered clinical trials in Patients With Type 2 Diabetes.
CAS:
1234703-40-2
Molecular Weight:
559.81
Formula:
C28H37N3O3S3
Chemical Name:
(1R, 2S)-2-cyclohexyl-1-(4-cyclopropylsulfonylphenyl)-N-[5-(2-pyrrolidin-1-ylethylsulfanyl)-1, 3-thiazol-2-yl]cyclopropane-1-carboxamide
Smiles :
O=C(NC1=NC=C(S1)SCCN1CCCC1)[C@@]1(C[C@H]1C1CCCCC1)C1C=CC(=CC=1)S(=O)(=O)C1CC1
InChiKey:
QIIVJLHCZUTGSD-CUBQBAPOSA-N
InChi :
InChI=1S/C28H37N3O3S3/c32-26(30-27-29-19-25(36-27)35-17-16-31-14-4-5-15-31)28(18-24(28)20-6-2-1-3-7-20)21-8-10-22(11-9-21)37(33,34)23-12-13-23/h8-11,19-20,23-24H,1-7,12-18H2,(H,29,30,32)/t24-,28-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Birtamimab} MedChemExpress|{Birtamimab} Neuronal Signaling|{Birtamimab} Protocol|{Birtamimab} In stock|{Birtamimab} custom synthesis|{Birtamimab} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.{{Alkaline phosphatase} site|{Alkaline phosphatase} Metabolic Enzyme/Protease|{Alkaline phosphatase} Technical Information|{Alkaline phosphatase} Formula|{Alkaline phosphatase} manufacturer|{Alkaline phosphatase} Epigenetics}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23376608
Additional information:
LY-2608204 is an activator of glucokinase (GK) with an EC50 value of 42 nM. LY2608204 decreases plasma glucose in a dose-dependent manner at both fasted and postprandial glucose levels. In 2010, LY-2608204 was entered clinical trials in Patients With Type 2 Diabetes.|Product information|CAS Number: 1234703-40-2|Molecular Weight: 559.81|Formula: C28H37N3O3S3|Chemical Name: (1R, 2S)-2-cyclohexyl-1-(4-cyclopropylsulfonylphenyl)-N-[5-(2-pyrrolidin-1-ylethylsulfanyl)-1, 3-thiazol-2-yl]cyclopropane-1-carboxamide|Smiles: O=C(NC1=NC=C(S1)SCCN1CCCC1)[C@@]1(C[C@H]1C1CCCCC1)C1C=CC(=CC=1)S(=O)(=O)C1CC1|InChiKey: QIIVJLHCZUTGSD-CUBQBAPOSA-N|InChi: InChI=1S/C28H37N3O3S3/c32-26(30-27-29-19-25(36-27)35-17-16-31-14-4-5-15-31)28(18-24(28)20-6-2-1-3-7-20)21-8-10-22(11-9-21)37(33,34)23-12-13-23/h8-11,19-20,23-24H,1-7,12-18H2,(H,29,30,32)/t24-,28-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|