Product Name :
Tiliroside
CAS No.:
20316-62-5
Purity :
> 99%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
OC1C(O)C(COC(=O)\C=C\C2=CC=C(O)C=C2)OC(OC3=C(OC4=C(C(=CC(=C4)O)O)C3=O)C5=CC=C(O)C=C5)C1O
Product Description :
Tiliroside shows a hepatoprotective effect against D-galactosamine (D-GalN)/lipopolysaccharide (LPS)-induced liver injury in mice.Tiliroside enhances fatty acid oxidation via the enhancement adiponectin signaling associated with the activation of both AMP-activated protein kinase and peroxisome proliferator-activated receptor α and ameliorates obesity-induced metabolic disorders. Tiliroside shows very potent anti-complement activity (IC50=5.4 x 10(-5) M) on the classical pathway of the complement system.Tiliroside and gnaphaliin are antioxidants against in vitro Cu 2+ -induced LDL oxidation in the same order of magnitude compared to that of the reference drug, probucol.Tiliroside has anti-diabetic effects, the effects at least partially mediated through inhibitory effects on carbohydrate digestion and glucose uptake in the gastrointestinal tract.{{1092351-10-4} medchemexpress|{1092351-10-4} Biological Activity|{1092351-10-4} Formula|{1092351-10-4} supplier} Tiliroside has in vivo anti-inflammatory activity, it can inhibit neuroinflammation in BV2 microglia through a mechanism involving TRAF-6-mediated activation of NF-κB and p38 MAPK signalling pathways.
Formula:
C30H26O13
Molecular Weight :
594.52
Synonyms:
Additional Information:
|CAS No. 20316-62-5 ; |Formula C30H26O13 ; |Molecular Weight 594.52 ; |SMILES OC1C(O)C(COC(=O)\C=C\C2=CC=C(O)C=C2)OC(OC3=C(OC4=C(C(=CC(=C4)O)O)C3=O)C5=CC=C(O)C=C5)C1O ; |Target NFkB ; |Product Description Tiliroside shows a hepatoprotective effect against D-galactosamine (D-GalN)/lipopolysaccharide (LPS)-induced liver injury in mice.{{1222998-36-8} site|{1222998-36-8} Biological Activity|{1222998-36-8} Formula|{1222998-36-8} custom synthesis} Tiliroside enhances fatty acid oxidation via the enhancement adiponectin signaling associated with the activation of both AMP-activated protein kinase and peroxisome proliferator-activated receptor α and ameliorates obesity-induced metabolic disorders.PMID:30000740 Tiliroside shows very potent anti-complement activity (IC50=5.4 x 10(-5) M) on the classical pathway of the complement system.Tiliroside and gnaphaliin are antioxidants against in vitro Cu 2+ -induced LDL oxidation in the same order of magnitude compared to that of the reference drug, probucol.Tiliroside has anti-diabetic effects, the effects at least partially mediated through inhibitory effects on carbohydrate digestion and glucose uptake in the gastrointestinal tract.Tiliroside has in vivo anti-inflammatory activity, it can inhibit neuroinflammation in BV2 microglia through a mechanism involving TRAF-6-mediated activation of NF-κB and p38 MAPK signalling pathways. ; |Purity > 99% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO