Product Name :
Xanthine amine congener dihydrochloride

Description:
Xanthine amine congener dihydrochloride (XAC dihydrochloride) is a potent Adenosine A1 receptor and A2 receptor antagonist with IC50 values of 1.8 and 114 nM, respectively. Xanthine amine congener acts as a convulsant agent in mice model.

CAS:
1962928-23-9

Molecular Weight:
501.41

Formula:
C21H30Cl2N6O4

Chemical Name:
N-(2-aminoethyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)phenoxy]acetamide dihydrochloride

Smiles :
Cl.Cl.CCCN1C(=O)C2NC(=NC=2N(CCC)C1=O)C1C=CC(=CC=1)OCC(=O)NCCN

InChiKey:
KGNTWECSNGWFKE-UHFFFAOYSA-N

InChi :
InChI=1S/C21H28N6O4.2ClH/c1-3-11-26-19-17(20(29)27(12-4-2)21(26)30)24-18(25-19)14-5-7-15(8-6-14)31-13-16(28)23-10-9-22;;/h5-8H,3-4,9-13,22H2,1-2H3,(H,23,28)(H,24,25);2*1H

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
Xanthine amine congener dihydrochloride (XAC dihydrochloride) is a potent Adenosine A1 receptor and A2 receptor antagonist with IC50 values of 1.8 and 114 nM, respectively. Xanthine amine congener acts as a convulsant agent in mice model.{{Hirudin} web|{Hirudin} Metabolic Enzyme/Protease|{Hirudin} Purity & Documentation|{Hirudin} In Vivo|{Hirudin} custom synthesis|{Hirudin} Epigenetic Reader Domain} |Product information|CAS Number: 1962928-23-9|Molecular Weight: 501.41|Formula: C21H30Cl2N6O4|Chemical Name: N-(2-aminoethyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)phenoxy]acetamide dihydrochloride|Smiles: Cl.Cl.CCCN1C(=O)C2NC(=NC=2N(CCC)C1=O)C1C=CC(=CC=1)OCC(=O)NCCN|InChiKey: KGNTWECSNGWFKE-UHFFFAOYSA-N|InChi: InChI=1S/C21H28N6O4.2ClH/c1-3-11-26-19-17(20(29)27(12-4-2)21(26)30)24-18(25-19)14-5-7-15(8-6-14)31-13-16(28)23-10-9-22;;/h5-8H,3-4,9-13,22H2,1-2H3,(H,23,28)(H,24,25);2*1H|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{SKF 81297} MedChemExpress|{SKF 81297} Agonist|{SKF 81297} Activator|{SKF 81297} Purity & Documentation|{SKF 81297} In Vivo|{SKF 81297} custom synthesis} |Shelf Life: ≥12 months if stored properly.PMID:33100110 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Xanthine amine congener dihydrochloride is more potent as a convulsant than either caffeine or theophyllin in infusion studies at the dosage 39.8 mg/kg. XAC has no effects by administering the drug via an i.p. injection, the seizure threshold >1000 mg/kg.|Products are for research use only. Not for human use.|

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