Product Name :
KHK-IN-2
Description:
KHK-IN-2 is a potent and selective ketohexokinase (KHK) inhibitor with an IC50 of 0.45 μM.
CAS:
2135304-43-5
Molecular Weight:
371.33
Formula:
C16H18F3N4O3
Chemical Name:
6-[(3S)-3,4-dihydroxypyrrolidin-1-yl]-2-[(3S)-3-hydroxy-3-methylpyrrolidin-1-yl]-4-(trifluoromethyl)pyridine-3-carbonitrile
Smiles :
C[C@@]1(O)CN(CC1)C1=NC(=CC(=C1C#N)C(F)(F)F)N1C[C](O)[C@@H](O)C1 |^1:21|
InChiKey:
XMQCHKGRGRRDKJ-NHYWBVRUSA-N
InChi :
InChI=1S/C16H18F3N4O3/c1-15(26)2-3-22(8-15)14-9(5-20)10(16(17,18)19)4-13(21-14)23-6-11(24)12(25)7-23/h4,11,24-26H,2-3,6-8H2,1H3/t11-,15-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Clemizole} site|{Clemizole} Inhibitor|{Clemizole} Immunology/Inflammation|{Clemizole} Purity & Documentation|{Clemizole} Formula|{Clemizole} custom synthesis}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Pantoprazole} site|{Pantoprazole} Autophagy|{Pantoprazole} Biological Activity|{Pantoprazole} Purity|{Pantoprazole} custom synthesis|{Pantoprazole} Autophagy}
Additional information:
KHK-IN-2 is a potent and selective ketohexokinase (KHK) inhibitor with an IC50 of 0.PMID:33176473 45 μM.|Product information|CAS Number: 2135304-43-5|Molecular Weight: 371.33|Formula: C16H18F3N4O3|Chemical Name: 6-[(3S)-3,4-dihydroxypyrrolidin-1-yl]-2-[(3S)-3-hydroxy-3-methylpyrrolidin-1-yl]-4-(trifluoromethyl)pyridine-3-carbonitrile|Smiles: C[C@@]1(O)CN(CC1)C1=NC(=CC(=C1C#N)C(F)(F)F)N1C[C](O)[C@@H](O)C1 |^1:21||InChiKey: XMQCHKGRGRRDKJ-NHYWBVRUSA-N|InChi: InChI=1S/C16H18F3N4O3/c1-15(26)2-3-22(8-15)14-9(5-20)10(16(17,18)19)4-13(21-14)23-6-11(24)12(25)7-23/h4,11,24-26H,2-3,6-8H2,1H3/t11-,15-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 250 mg/mL (671.43 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|