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Neurotensin 1 receptor (NTS1) polyclonal antibody
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The subtype 1 neurotensin receptor (NTS1) is a seven-transmembrane domain containing G protein coupled receptor (GPCR) that mediates most of the known effects of neurotensin. NTS1 activates a phosphatidylinositol-calcium second messenger system in the central and peripheral nervous systems, mediating such functions as hypotension, hyperglycemia, hypothermia, antinociception, and the regulation of intestinal motility and secretion. NTS1 signaling is primarily mediated via coupling to Gq/G11 family G proteins, although coupling of NTS1 through Gs and Gi/o family proteins has been shown to modulate both adenylate and guanylate cyclase activity.{{259793-96-9} site|{259793-96-9} Technical Information|{259793-96-9} Purity|{259793-96-9} manufacturer} Western blot analysis: MW marker (1) and 20µg rat kidney extract (2) probed with Neurotensin Receptor 1 (NTS1) pAb.{{2574591-89-0} MedChemExpress|{2574591-89-0} Protocol|{2574591-89-0} Formula|{2574591-89-0} supplier} Western blot analysis: MW marker (1) and 20µg rat kidney extract (2) probed with Neurotensin Receptor 1 (NTS1) pAb.PMID:20301678
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| Application IHC, WB | Application Notes Detects a band of ~40kDa. by Western blot. | Crossreactivity Predicted species reactivity based on epitope sequence homology: bovine, dog, rhesus macaque. | Formulation Liquid. In PBS containing 50% glycerol and 0.01% sodium azide. | Host Rabbit | Immunogen Synthetic peptide corresponding to the sequence near the N-terminus of human Neurotensin 1 Receptor (NTS1). | Species Reactivity Human, Mouse, Rat | UniProt ID P30989 | Unit of Measure (UM) µg